July 21, 2019


Stem Cell Therapy for Alpha-1 Antitrypsin Deficiency-Hope Medical Group

Alpha-1 Antitrypsin Deficiency (Alpha-1) is a genetic condition that is passed on by parents to their children through their genes and can cause serious liver disease in children and liver and/or lung disease in adults.

Alpha-1 antitrypsin is a protein that is produced mostly in the liver. Its primary function is to protect the lungs from neutrophil elastase. Neutrophil elastase is an enzyme that normally serves a useful purpose in lung tissue-it digests damaged or aging cells and bacteria to promote healing. However, if left unchecked, it will also attack healthy lung tissue. Alpha-1 antitrypsin, in sufficient amounts, will trap and destroy neutrophil elastase before it has a chance to begin damaging the delicate lung tissue. Consequently, if an individual doesn't have enough alpha-1 antitrypsin, the enzyme goes unchecked and attacks the lung.

Family history of lung disease or liver disease symptoms:

. Shortness of breath
.Wheezing or non-responsive asthma
. Coughing with or without sputum (phlegm) production
. Recurring respiratory infections
. Rapid deterioration of lung function
. Unexplained liver problems and /or elevated liver enzymes

Alpha-1 Carriers with only one abnormal copy of the gene can produce enough protein to stay healthy, especially if they do not smoke. However, people with two damaged copies of the gene can't produce enough alpha-1 antitrypsin, which can cause several conditions. They are often diagnosed with emphysema as their primary disease. Other common diagnoses include COPD (chronic obstructive pulmonary disease), asthma, chronic bronchitis, and bronchiectasis. Alphas are usually quite susceptible to lung infections. In the patient with Alpha-1, any of these conditions can cause further damage if they aren't treated right away.

Some patients with Alpha-1 develop is cirrhosis of the liver, the condition arises from a single point mutation in both copies of the gene that codes for alpha-1 antitrypsin a mutation that causes the protein to form ordered polymers in hepatocytes, eventually leading to cirrhosis. This scarring of healthy liver tissue affects infants with Alpha-1. In past, liver transplant is the only option available for advanced disease.

Non-surgical & Non-drug Therapy Option

Adult stem cell therapy via Umbilical cord mesenchymal stem cells (UCMSC) offers the possibility of generating unlimited quantities of cells for transplantation. By correcting the genetic defect underlying Z-allele α1-antitrypsin deficiency. When the stem cells were injected into the livers, they quickly became distributed throughout the organ and integrated into the parenchyma.

To repair damaged functional cells, Stem Cell Therapy often is applied. Stem Cell Treatment is an advanced medical treatment and the application of it is based on the original cells which can differentiate into different functional cells when we cultivate them with specific nutrient solution. Through Stem Cell Therapy, liver functions can be recovered effectively and because of this, sufferers can live freely again.

Stem Cell Treatment is a new breakthrough in the world. Can it treat cirrhosis? The answer is certainly. Stem cell is able to restore damaged cells, repair cells function and treat diseases due to the damaged cells. Patients will not suffer from the operational pain if they receive Stem Cell Transplantation. Stem cells are able to rebuild the function of liver function. It is a better choice to treat liver with Stem Cell Transplantation.

Stem cell has the ability to change the treatment of liver. In many cases, patients have got rid of medicine. Stem cells entering liver with blood circulation can renew epithelial cell of liver tubules and interstitial cell caused by bacterium, virus infection and chronic inflammation. And it can strengthen immune competence of organism to fight with etiological factor and prevent from developing liver disease.

 For more information on stem cell treatment for copd, please complete a medical form here or visit http://hopestemcell.com/

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