July 18, 2018

 

Immunotherapy for Thyroid Cancer-Hope Medical Group

Stem cell Cancer Immunotherapy for thyroid cancer

Disadvantages of Radiotherapy & Chemotherapy
Chemotherapy works by interrupting cell division in cells that are multiplying quickly. Since cancer cells reproduce at an abnormally fast rate, they are affected by chemotherapy. Several cycles are needed to catch more cells, since not all of them will be dividing on the day you get chemotherapy. Unfortunately, other cells in your body also reproduce quickly enough to be affected by the treatment. Hair follicles shut down, which means your hair either falls out or does not grow. The linings of the mouth, stomach, and intestines also contain cells that multiply rapidly. These cells are disrupted by chemotherapy, which can cause mouth sores, a "burned tongue" sensation, nausea, constipation, hemorrhoids, and diarrhea.
The disadvantage of radiotherapy is also the worry that the cancer will come back.

Non-surgical treatments
DC + CIK cells can effectively cure cancer.
Today, tumors can be detected early and removed with advanced surgery and treatment, but current therapies cannot prevent or eradicate cancer after metastatic spread to distant organs. The prognosis is very poor if Cancer spreads to the brain. As a shielded "sanctuary site," the brain may harbor cancer cells which resist current treatments and can develop into satellite tumors, known as metastases, long after chemo-, radiation, or immuno- therapies have been applied. The patient's situation can be managed in the clinic only for a few weeks or months before becoming fatal.
Our DC+CIK cancer treatment provides new hope for patients, through an innovative approach based on stem cells, the body's own natural mechanism for healing and regeneration.
Cytokine-induced killer (CIK) cells are important immune cells, and dendritic cells (DC) can be induced to be co-cultured with CD3 + CD56 + (NKT) phenotype main groups of T-killer cells (DCCIK). Immunotherapy in cancer patients showed a broad spectrum of killing tumor cells, its function and use of exogenous split-mediated tumor cell material, tumor-associated antigen-activated DC, CIK cells co-cultured cells different, is not major histocompatibility complex (MHC) restricted, and there is a strong anti-tumor immune activity. It also significantly reduces the immune tolerance of cancer patients, a decrease of T suppressor cells (Treg1 immunosuppression and effectively prevent the generation of autoimmune disease in patients.

In short, DC+CIK cells in the human body's own immune system enhance and rebuild its immune system, automatically identify and track tumor cells, and transmit this information to patients own immune cells, promoting their activation and proliferate to eliminate residual metastatic lesions, prevent spread and recurrence of cancer and enhance immunity. This improves the quality of life of patients, ultimately prolonging the patients life for years.
 

 

Thyroid Cancer occurs in the cells of the thyroid — a butterfly-shaped gland located at the base of your neck, just below your Adam's apple. Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight.

 

Although thyroid cancer isn't common in the United States, rates seem to be increasing. Doctors think this is because new technology is allowing them to find small thyroid cancers that may not have been found in the past.

 

Most cases of thyroid cancer can be cured with treatment.

Symptoms

 

Thyroid cancer typically doesn't cause any signs or symptoms early in the disease. As thyroid cancer grows, it may cause:

 

A lump that can be felt through the skin on your neck

 

Changes to your voice, including increasing hoarseness

Difficulty swallowing

Pain in your neck and throat

Swollen lymph nodes in your neck

Causes

 

It's not clear what causes thyroid cancer. Thyroid cancer occurs when cells in your thyroid undergo genetic changes (mutations). The mutations allow the cells to grow and multiply rapidly. The cells also lose the ability to die, as normal cells would. The accumulating abnormal thyroid cells form a tumor. The abnormal cells can invade nearby tissue and can spread throughout the body.

Types of thyroid cancer
The type of thyroid cancer determines treatment and prognosis. Types of thyroid cancer include:

 

Papillary thyroid cancer. The papillary type of thyroid cancer is the most common, making up about 80 percent of all thyroid cancer diagnoses.

 

 

 

Follicular thyroid cancer. Follicular thyroid cancer also includes Hurthle cell cancer.

 

 

 

Medullary thyroid cancer. Medullary thyroid cancer may be associated with inherited genetic syndromes that include tumors in other glands. However, most medullary thyroid cancers are sporadic, meaning they aren't associated with inherited genetic syndromes.

 

 

 

Anaplastic thyroid cancer. The anaplastic type of thyroid cancer is very rare, aggressive and very difficult to treat.

 

 

 

Thyroid lymphoma. Thyroid lymphoma begins in the immune system cells in the thyroid. Thyroid lymphoma is very rare.

Risk factors

Factors that may increase the risk of thyroid cancer include:

 

Exposure to high levels of radiation. Examples of high levels of radiation include those that come from radiation treatment to the head and neck and from fallout from such sources as nuclear power plant accidents or weapons testing.

 

 

 

Personal or family history of goiter. Goiter is a noncancerous enlargement of the thyroid.

 

 

 

Certain inherited genetic syndromes. Genetic syndromes that increase the risk of thyroid cancer include familial medullary thyroid cancer, multiple endocrine neoplasia and familial adenomatous polyposis.

Complications

Thyroid cancer that comes back
 

Despite treatment, thyroid cancer can return, even if you've had your thyroid removed. This could happen if microscopic cancer cells spread beyond the thyroid before it's removed. Thyroid cancer recurrence can occur decades after thyroid cancer treatment.

Thyroid cancer may recur in:

 

Lymph nodes in the neck

 

Small pieces of thyroid tissue left behind during surgery

Other areas of the body — most often the lungs or the bones

 

 

Thyroid cancer that recurs can be treated. Your doctor may recommend periodic blood tests or thyroid scans to check for signs of a thyroid cancer recurrence.

Treatment

 

Cancer is a class of diseases characterized by out-of-control cell growth. There are over 100 different types of cancer, and each is classified by the type of cell that is initially affected.

 

Cancer harms the body when damaged cells divide uncontrollably to form lumps or masses of tissue called tumors (except in the case of leukemia where cancer prohibits normal blood function by abnormal cell division in the blood stream). Tumors can grow and interfere with the digestive, nervous, and circulatory systems, and they can release hormones that alter body function. Tumors that stay in one spot and demonstrate limited growth are generally considered to be benign.

More dangerous, or malignant, tumors form when two things occur:

A cancerous cell manages to move throughout the body using the blood or lymph systems, destroying healthy tissue in a process called invasion

That cell manages to divide and grow, making new blood vessels to feed itself in a process called angiogenesis.

When a tumor successfully spreads to other parts of the body and grows, invading and destroying other healthy tissues, it is said to have metastasized. This process itself is called metastasis, and the result is a serious condition that is very difficult to treat.

Cancer is ultimately the result of cells that uncontrollably grow and do not die. Normal cells in the body follow an orderly path of growth, division, and death. Programmed cell death is called apoptosis, and when this process breaks down, cancer begins to form. Unlike regular cells, cancer cells do not experience programmatic death and instead continue to grow and divide. This leads to a mass of abnormal cells that grows out of control.

Cancer symptoms are quite varied and depend on where the cancer is located, where it has spread, and how big the tumor is. Some cancers can be felt or seen through the skin - a lump on the breast or testicle can be an indicator of cancer in those locations. Skin cancer (melanoma) is often noted by a change in a wart or mole on the skin. Some oral cancers present white patches inside the mouth or white spots on the tongue.

Other cancers have symptoms that are less physically apparent. Some brain tumors tend to present symptoms early in the disease as they affect important cognitive functions. Pancreas cancers are usually too small to cause symptoms until they cause pain by pushing against nearby nerves or interfere with liver function to cause a yellowing of the skin and eyes called jaundice. Symptoms also can be created as a tumor grows and pushes against organs and blood vessels. For example, colon cancers lead to symptoms such as constipation, diarrhea, and changes in stool size. Bladder or prostate cancers cause changes in bladder function such as more frequent or infrequent urination.

As cancer cells use the body's energy and interfere with normal hormone function, it is possible to present symptoms such as fever, fatigue, excessive sweating, anemia, and unexplained weight loss. However, these symptoms are common in several other maladies as well. For example, coughing and hoarseness can point to lung or throat cancer as well as several other conditions.

When cancer spreads, or metastasizes, additional symptoms can present themselves in the newly affected area. Swollen or enlarged lymph nodes are common and likely to be present early. If cancer spreads to the brain, patients may experience vertigo, headaches, or seizures. Spreading to the lungs may cause coughing and shortness of breath. In addition, the liver may become enlarged and cause jaundice and bones can become painful, brittle, and break easily. Symptoms of metastasis ultimately depend on the location to which the cancer has spread.

There are five broad groups that are used to classify cancer.

Carcinomas are characterized by cells that cover internal and external parts of the body such as lung, breast, and colon cancer.

Sarcomas are characterized by cells that are located in bone, cartilage, fat, connective tissue, muscle, and other supportive tissues.

Lymphomas are cancers that begin in the lymph nodes and immune system tissues.

Leukemias are cancers that begin in the bone marrow and often accumulate in the bloodstream.

Adenomas are cancers that arise in the thyroid, the pituitary gland, the adrenal gland, and other glandular tissues.

Cancers are often referred to by terms that contain a prefix related to the cell type in which the cancer originated and a suffix such as -sarcoma, -carcinoma, or just -oma. Common prefixes include:

Adeno- = gland

Chondro- = cartilage

Erythro- = red blood cell

Hemangio- = blood vessels

Hepato- = liver

Lipo- = fat

Lympho- = white blood cell

Melano- = pigment cell

Myelo- = bone marrow

Myo- = muscle

Osteo- = bone

Uro- = bladder

Retino- = eye

Neuro- = brain

 

Early detection of cancer can greatly improve the odds of successful treatment and survival. Physicians use information from symptoms and several other procedures to diagnose cancer. Imaging techniques such as X-rays, CT scans, MRI scans, PET scans, and ultrasound scans are used regularly in order to detect where a tumor is located and what organs may be affected by it. Doctors may also conduct an endoscopy, which is a procedure that uses a thin tube with a camera and light at one end, to look for abnormalities inside the body.

 

Extracting cancer cells and looking at them under a microscope is the only absolute way to diagnose cancer. This procedure is called a biopsy. Other types of molecular diagnostic tests are frequently employed as well. Physicians will analyze your body's sugars, fats, proteins, and DNA at the molecular level. For example, cancerous prostate cells release a higher level of a chemical called PSA (prostate-specific antigen) into the bloodstream that can be detected by a blood test. Molecular diagnostics, biopsies, and imaging techniques are all used together to diagnose cancer.

 For more information on stem cell cancer immunotherapy for thyroid cancer, please complete a medical form here or visit http://www.hopestemcell.com/cancer-immunology

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