September 25, 2018

 

Immunotherapy for Bone Marrow Cancer-Hope Medical Group

Disadvantages of Radiotherapy & Chemotherapy
Chemotherapy works by interrupting cell division in cells that are multiplying quickly. Since cancer cells reproduce at an abnormally fast rate, they are affected by chemotherapy. Several cycles are needed to catch more cells, since not all of them will be dividing on the day you get chemotherapy. Unfortunately, other cells in your body also reproduce quickly enough to be affected by the treatment. Hair follicles shut down, which means your hair either falls out or does not grow. The linings of the mouth, stomach, and intestines also contain cells that multiply rapidly. These cells are disrupted by chemotherapy, which can cause mouth sores, a "burned tongue" sensation, nausea, constipation, hemorrhoids, and diarrhea.
The disadvantage of radiotherapy is also the worry that the cancer will come back.

Non-surgical treatments
DC + CIK cells can effectively cure cancer.
Today, tumors can be detected early and removed with advanced surgery and treatment, but current therapies cannot prevent or eradicate cancer after metastatic spread to distant organs. The prognosis is very poor if Cancer spreads to the brain. As a shielded "sanctuary site," the brain may harbor cancer cells which resist current treatments and can develop into satellite tumors, known as metastases, long after chemo-, radiation, or immuno- therapies have been applied. The patient's situation can be managed in the clinic only for a few weeks or months before becoming fatal.
Our DC+CIK cancer treatment provides new hope for patients, through an innovative approach based on stem cells, the body's own natural mechanism for healing and regeneration.
Cytokine-induced killer (CIK) cells are important immune cells, and dendritic cells (DC) can be induced to be co-cultured with CD3 + CD56 + (NKT) phenotype main groups of T-killer cells (DCCIK). Immunotherapy in cancer patients showed a broad spectrum of killing tumor cells, its function and use of exogenous split-mediated tumor cell material, tumor-associated antigen-activated DC, CIK cells co-cultured cells different, is not major histocompatibility complex (MHC) restricted, and there is a strong anti-tumor immune activity. It also significantly reduces the immune tolerance of cancer patients, a decrease of T suppressor cells (Treg1 immunosuppression and effectively prevent the generation of autoimmune disease in patients.

In short, DC+CIK cells in the human body's own immune system enhance and rebuild its immune system, automatically identify and track tumor cells, and transmit this information to patients own immune cells, promoting their activation and proliferate to eliminate residual metastatic lesions, prevent spread and recurrence of cancer and enhance immunity. This improves the quality of life of patients, ultimately prolonging the patients life for years.

 

Every man over 40 get a blood test called Prostate Specific Antigen to check for prostate cancer, prostate Specific Antigen is made by prostate cells and is released into the bloodstream. Large prostates have more PSA, so a rise in PSA means that the gland is enlarging rapidly, which can be a sign of cancer or that the prostate is irritated by infection. Any manipulation of the prostate raises blood PSA levels. PSA levels can be raised for several hours just by having your prostate checked by a physician (2,3), so PSA blood tests should be drawn before the doctor examines the prostate. Having a climax raises PSA for up to 48 hours (5,6,7,8,9,10,11,12). Infections raise PSA and there is no way to tell the difference between a PSA raised by cancer or by infection.

PSA can be classified into two different fractions called free and bound PSA. Free PSA is made by a normal prostate, while bound PSA is made primarily by prostate cancer cells. The usual rule is that if a man's PSA is above 4 (normal 0-4), the free PSA should be at least 18 percent of the total PSA. This rule usually holds for every situation except infection. The ratio of free PSA to bound PSA is the same for prostate cancer and infections.

PSA aka Prostate Specific Antigen is a protein enzyme produced in the prostate gland and released in to the blood stream thereafter. After a blood work analysis, the resulting PSA test score shows how much of this enzyme you're producing, and your probability of having prostate cancer.

Normal PSA Scores
- 15% of men with psa levels less than 4 ng/ml develop prostate cancer.
- 31% of men with prostate cancer screening between 4 - 10 ng/ml develop prostate cancer.
- 50% - 65% of men with psa scores over 10 ng/ml develop prostate cancer.
An important part of the your results is finding both the;
1. Total amount of PSA in your blood.
2. Ratio of free vs bound PSA.

Bone marrow is the spongy, soft tissue contained inside most bones. This tissue is made up of immature cells, which are known as stem cells, which develop into various types of blood cells such as: red blood cells, which help in carrying oxygen throughout the body; white blood cells, which are part of the immune system and therefore help in fighting infection; and platelets, which help in clotting blood. As red blood cell production requires iron, the body usually stores a large portion of its supply of iron in the bone marrow. Bone marrow cancer occurs when the cells that form blood become cancerous.

Usually bone marrow cancer occurs due to cancer spreading to the bone from some other organ, when it is referred to as secondary bone cancer. On examination under the microscope, these cancers bear a resemblance to the original tissue they came from, such as the lung, breast, prostate, and so on.


Primary bone marrow cancers, on the other hand, are the type that occurs in the bone marrow cells that form blood, and these are:


Multiple Myeloma: This is a type of bone marrow cancer that affects the plasma cells, which are a kind of white blood cells that occur in the bone marrow. The disease occurs due to the plasma cells growing abnormally. Normally, plasma cells produce antibodies. So, when these malignant or abnormal plasma cells divide and multiply rapidly, without order or control, as is the case in cancerous cells, it results in the production of huge amounts of abnormal antibodies, which accumulate in the blood as well as the urine. With the growth of the plasma cell tumor, the surrounding bone is also destroyed. These effects result in an impaired immune system, damage to the kidneys, and pain in the bones. The disease is referred to as multiple myeloma since it can affect multiple sites of the body where bone marrow occurs.

Leukemia: This disease occurs when the bone marrow produces white blood cells that are abnormal. Leukemia is a term that defines 4 different types of diseases: Acute Lymphocytic Leukemia, or ALL; Acute Myelogenous Leukemia, or AML; Chronic Lymphocytic Leukemia, or CLL; and Chronic Myelogenous Leukemia, or CML.

Acute myelogenous leukemia and acute lymphocytic are both made up of blast cells, referred to as myeloblasts or lymphoblasts. The term 'acute' is indicative of the disease progressing rapidly, in the absence of treatment. Chronic leukemia either does not have any blast cells or they are few, and it progresses comparatively slowly.

Lymphoma: This usually affects the lymphatic system, but sometimes can begin in the bone marrow. For example, Hodgkin lymphoma, which usually affects the lymph nodes, but can also affect the bone marrow.

For more information on stem cell immunotherapy for bone marrow cancer, please complete a medical form here or visit http://hopestemcell.com/cancer-immunology

 

 

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